Tuesday, November 21, 2006

 
_________Hexokinase
1. Glucose -------------> Glucose-6-phosphate
_________ATP -> ADP
_____________________phosphoglucose isomerase
2. Gluchose-6-phosphate -------------------------------> Fructose-6-phospate
______________________6-Phosphofructo-1-kinase
3. Fructose-6-phosphate -------------------------------> Fructose-1,6-bisphosphate
___________________________ATP -> ADP
_________________________Fructose bisphosphate aldolase
4. Fructose-1,6-bisphosphate ------------------------------------> Dihydroxyacetone
____________________________________________________Phosphate +
____________________________________________________Glyceraldehyde-3-
____________________________________________________phosphate
__________Triose phosphate isomerase
4.5. DHAP <--------------------------------> G3P
__________________________Glyceraldehyde-3-phosphate dehydrogenase
5. Glyceraldehyde-3-phosphate ---------------------------------------------------->
__________________________________Pi & NAD -> NADH + H+
__1,3-Bisphosphoglycerate
_______________________Phosphoglycerate kinase
6. 1,3-Bisphosphoglycerate -----------------------------> 3-phosphoglycerate
_____________________________ADP -> ATP
____________________Enolase
7. 3-phosphoglycerate -----------> Phosphoenolpyruvate + H2O
____________________Pyruvate Kinase
8. Phosphoenolpyruvate ------------------> Pyruvate
______________________ADP -> ATP

*Net products:
- 2 ATP
- 2 reduced NAD
* Irreversible steps:
- Hexokinase
- 6-Phosphofructo-1-kinase (PFK)
- Pyruvate kinase


# posted by yingliang @ 5:26 AM 0 comments

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